Thanks to RHMediadesk for his sick beats! This wouldn't have been possible without such a hot track. So here are some white girls (LBow, M-Squared, and Righteous MH Pain) rapping about biology.
Translation station about to begin
With these three steps your body will win
The point of translation is to make some protein
Use adenine, guanine, thymine, and uracil!
In the cytoplasm is where it be
Look a little closer and you will see
That tRNA has the anticodon bit
And mRNA has the codon [THATS LEGIT!]
Three different steps make up this thang
Its sure to go off with a bang
Initiation, elongation and still theres more
Termination wraps up this fantastic score
Initiation begins with start codon AUG
The direction is from five prime to three
Small ribosomal unit comes out to play
It moves down the strand of the mRNA
The first tRNA is up to bat
With anticodon UAC, man thats phat
Hydrogen bonding connect the two
Translation initiation complex foo
Thanks to a subunit of the large ribosome
Initiation factors bring it on home
Thats the first step, wasnt it great?
Onto elongation I cant wait!
Of amino acids there are plenty
As a matter of fact I count twenty
on five prime of tRNA
they wait till its bound at the site of A
Elongation factors bring it together
Hydrogen bonding, can it last forever?
Now amino acids must get their bond
Of this coming step, Ive grown quite fond
If P and A are full, polypeptide bonds can form
Ribosomes catalyse and make this the norm
The old tRNA is basically deceased
It moves to the E site where its released
Now for termination, three out of three
UAA, UGA, and UAG
These are the stop codons, they wont bite
The release factor fills the empty A site
Release factors catalyse the hydrolysis
Yo, polypeptide chain listen to this!
You are released into the cytoplasm
The lysis of the bonds creates this chasm
The polypeptide chains now floating free
With multiple chains, a protein it will be
The ribosome knows its time is done
The unit splits into two from one
Wasnt this fun? Thanks for coming out
This process is just like a round-a-bout
If you liked it a lot, just hold the phone
Cause its happening now, in every cell and bone
WORD.