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The Agonarch Rune is a random drop on the Dreadnaught. It can be picked up in Patrol. The idea of the Rune is fairly simple. All you have to do is pick up 7 Taken Major Kills over a week period (7 Days). However you have to complete it each day so if you skip out Tuesday then you will have to wait until the following Tuesday to kill that Boss. In this video I show you: how to charge the Agonarch Rune, what enemies to kill and how to do it all quickly. Once the Rune is fully charged you can put it into the hidden Agonarch chest (You can find that in this video: https://www.youtube.com/watch?v=oT8ywywZD98). You will need to complete the Agonarch Rune and all it's tasks in order to unlock the Calcified Fragment XXXVI. It's also worth noting that this is unique to each of your characters and not your profile so you can unlock the chest 3 times in one week. Hopefully you enjoyed the video or/and found it helpful